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TRIS, TRIZMA, Tris(hydroxymethyl)aminomethane, 99.8%
CAS Number: 77-86-1
Molecular Formula: C4H11NO3
Molecular Weight: 121.14
IUPAC Name: 2-Amino-2-hydroxymethyl-propane-1,3-diol
Other Names: TRIS, Tris, Tris base, Tris buffer, Trizma, Trisamine, THAM, Tromethamine, Trometamol, Tromethane, Trisaminol
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Tris or Tris(hydroxymethyl)aminomethane or THAM is an organic compound with the formula (HOCH2)3CNH2. Tris is extensively used in biochemistry and molecular biology.
In biochemistry, Tris is widely used as a component of buffer solutions, such as in TAE and TBE buffer, especially for solutions of nucleic acids. It contains a primary amine and thus undergoes the reactions associated with typical amines, e.g. condensations with aldehydes.
